Orbitrap Fusion Lumos Tribrid Mass Spectrometer

Description

Description The Thermo Scientific Orbitrap Fusion Lumos Tribrid mass spectrometer is the industry-leading high-performance mass spectrometer with enhanced sensitivity facilitated by a new High Capacity Transfer Tube, Electrodynamic Ion Funnel, Advanced Quadrupole Technology, Advanced Vacuum Technology, and ETD HD.

Novel Orbitrap Fusion Lumos MS Features ◾Novel high-sensitivity API interface combines a High Capacity Transfer Tube and an Electrodynamic Ion Funnel for increased ion flux and lower limits of detection ◾Advanced Active Beam Guide prevents neutrals and high velocity clusters from entering the resolving quadrupole ◾Advanced Quadrupole Technology combines high selectivity and efficiency of transfer for selected ions symmetrically across the isolation window ◾Advanced Vacuum Technology improves transmission of high molecular weight ions to the Orbitrap analyzer ◾Novel ETD HD—high dynamic range ETD provides significantly increased fragment ion coverage

Established Tribrid MS Features ◾Tribrid architecture — includes quadrupole mass filter, linear ion trap and Orbitrap mass analyzers ◾Ultrahigh resolving power up to 500,000 FWHM, with isotopic fidelity up to 240,000 FWHM at m/z 200 ◾Acquisition rates of up to 20 Hz for both Orbitrap and linear ion trap MSn analyses ◾Full parallelization of MS and MSn analyses with intelligent ADAPT™ (All Dynamically Available Parallelizable Time) technology ◾Synchronous Precursor Selection (SPS) for MS and MSn experiments significantly increases the number of peptides and proteins identified and improves quantitative accuracy when using isobaric mass tags ◾Flexibility of fragmentation — CID, HCD and optional ETD and EThcD available at any stage of MSn with detection in either the Orbitrap or linear ion trap detector enables detailed structure determination of metabolites, glycans and other small molecules ◾Universal Method provides maximal peptide identifications without method optimization for samples of unknown concentration, reducing sample and instrument time requirements for routine peptide identifi cation experiments ◾Intuitive and flexible drag-and-drop user interface simplifies method development and enables unique and complex workflows