Chemistry NMR Service

Description

The Chemistry Nuclear Magnetic Resonance (NMR) Facility is housed in the Wolfson Suite of the Bedson Building; this underwent a major refurbishment in 2014 at a cost of over £1.3M and now hosts four NMR Spectrometers including a 700 MHz equipped with a nitrogen-cooled cryoprobe. The Spectrometers are equipped with a range of probes and are able to observe almost all NMR-active nuclei and perform the most demanding NMR experiments.

1D and 2D solution The full range of 1D and 2D solution NMR experiments are offered at frequencies of 300, 400, 500 and 700 MHz according to requirements. The cryoprobe equipped 700 MHz NMR machine is highly sensitive and is ideal for obtaining high-resolution spectra of compounds where sample quantity is an issue (e.g. natural product work). As well as the standard 1H and 13C NMR experiments, we are able to observe virtually all NMR active nuclei including 2H, 7Li, 11B, 17O, 19F, 27Al, 29Si, 31P, 51V, 95Mo, 103Rh, 113Cd, 119Sn, 183W, 195Pt and 207Pb.

2D Several 2D experiments are available including COSY, TOCSY, HMBC, HMQC, NOESY and ROESY.

Variable Temperature NMR Spectroscopy We routinely do Variable Temperature NMR Spectroscopy observing various nuclei at temperatures between -130 and +145 °C.